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HDR 1000 Plus Well Chamber

The HDR 1000 Plus Well Chamber*, REF 90008, precisely calibrates radioactive sources used for cancer treatment. The HDR 1000 Plus is the standard instrument for independently verifying prescribed patient dose. This verification helps protect the hospital from misadministration and liability. The HDR 1000 Plus is an air communicating chamber so there is no inaccuracy due to an undetected gas leak as in a pressurized chamber. Performance of the HDR 1000 Plus has been validated in over 30 publications.

The HDR 1000 Plus is ideal for low dose rate and high dose rate brachytherapy. Source holders are available for most existing isotopes available on the market today. If we do not list a source holder for the isotope you wish to measure, contact us and we will develop one for you.

High Dose Rate 192Ir Calibrations :

Source Holder for High Dose Rate Iridium, REF 70010, has a 2.2mm opening for the catheter. A rubber O-ring secures the catheter with a uniform constricting pressure to prevent any movement of the catheter.

The calibration procedure is easy and uncomplicated. The time required for calibration is only a fraction of that required for thimble ion chamber techniques.

High Dose Rate 192Ir Quality Assurance Test :

Perform the following crucial tests:

  • Source positioning verification to 0.3mm
  • Timer accuracy
  • Consistency of source activity

The benefits are:

  • Fast, 10-15 minute procedure
  • No films and development procedures
  • No multiple distance estimates
Quality Assurance Tool, REF 70008, tightly collimates the radiation received by the HDR1000 Plus to a narrow plane. Three short measurements are taken as the 192lr source is advanced to the 4mm opening.

Wall Mounted Bracket, REF 70007, secures the HDR 1000 Plus next to your afterloader for periodic quality assurance checks for verification of source presence, source strength, calibration accuracy, and timer consistency.

Individual Seed Calibration for Prostate Cancer Treatment :

Source Holder for Single Seed Measurements, REF 70016 This insert has a 1.2mm inner diameter Teflon® tube which positions an individual iodine, palladium, iridium, or gold seed at the most sensitive area of the HDR 1000 Plus. The smooth Teflon tube allows easy removal of the seed.

This source holder can be calibrated for several iodine and palladium isotopes at the University of Wisconsin ADCL. Only one source holder needs to be purchased for these multiple calibrations.

Batch Assay Measurements :

Source Holder for Seed Batch Assay, REF 70022 LDR brachytherapy treatment for prostate cancer requires high numbers of seeds. A treatment center may receive up to 500 seeds if several cases are imminent. Individual seed calibration can be time consuming and cumbersome. TG-40, referenced above, recommends a random sampling of at least 10% of the seeds.

Source Holder 70022 provides multiple seed measurements for up to 500 of the iodine or palladium seeds typically used for prostate cancer treatment.

This Source Holder positions seeds at the most sensitive area of the HDR 1000 Plus. If you have Source Holder 70016 with an ADCL calibration for the isotope being measured, you may use that calibration in conjunction with Source Holder 70022.


Self absorption resulting from a large number of seeds being placed in the insert is significant. Because of this self absorption, correction factors must be experimentally obtained for each type of LDR seed used. This method is described in detail in Med. Phys. 22 (9) Sept. 1995. Note: a correction factor for iodine and palladium, as shown in Fig. 2 of this article, should be determined for each individual well chamber upon receipt of the chamber.


Independent Verification :

Many manufacturers of brachytherapy seeds recommend independent verification of their source strengths. The AAPM does also, "Every institution practicing brachytherapy shall have a system for measuring source strength with secondary traceability for all source types used in its practice. Prior to using newly received sources for treatment, the vendor supplied (with the exceptions noted in the preceding paragraph) calibrations must be verified as per Task Group No. 40 recommendations. The institution should compare the manufacturer's stated value with the institution's standard". "Well-type ionization chambers make it easy to establish source calibrations with one of these traceabilities". From Code of practice for brachytherapy physics: Report of AAPM Radiation Therapy Committee Task Group No. 56. Med. Phvs. 24(10), Oct. 1997